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2022 MLB World Series Final Betting Tips & Predictions | Astros Vs. Phillies (Bo7, October 28 – November 5)

Major League Baseball has reached a crescendo in 2022 with the arrival of this year’s World Series Final.
We preview each team’s run to the finals before breaking down some of the betting odds and giving our expert picks and analysis on the best bets to make this World Series.
Philadelphia Phillies Vs. Houston Astros: Schedule & Venue
Event: | 2022 World Series Finals, Best-of-Seven Series |
Venues: | Minute Maid Park (Houston) and Citizens Bank Park (Philadelphia) |
Date: | Friday, 28 October to Saturday, 5 November, 2022 |
Overall Odds to Win 2022 World Series
Here’s a look at the overall outright 2022 World Series odds:
- Houston Astros to win @ 1.50 (1/2)
- Philadelphia Phillies to win @ 2.50 (6/4)
Bookies across the best betting sites for MLB are picking the 2022 World Series to be a tight one. The Houston Astros are slight favorites to win with odds of 1.50 (1/2), but the Philadelphia Phillies are nipping at their heels in most bookmakers, sitting on 2.50 (6/4) heading into the weekend.
Understanding the 2022 World Series
The World Series is a sporting event steeped in history, having first occurred in 1903. Teams across America and Canada are split into two divisions, with the two championship teams playing each other in a best-of-seven World Series final.
Here’s a look at the past 5 winners of the World Series:
- 2017 — Houston Astros
- 2018 — Boston Red Sox
- 2019 — Washington Nationals
- 2020 — Los Angeles Dodgers
- 2021 — Atlanta Braves
The last eight years have seen eight different winners of the World Series. Can the Philadelphia Phillies make it nine in nine?
Houston Astros Path to the Final
The Houston Astros last won the World Series in 2017 and have been beaten finalists in two of the past three seasons.
They will be looking to go one better in 2022 than last year and have strung together an impressive campaign to date. Qualifying for the post season with a record of 105-56, the Houston Astros have maintained a clean slate in knockout baseball this year, sweeping the Mariners 3-0 in the AL Division Series and the Yankees 4-0 in the AL Championship Series.
Only four more wins stand between them and the World Series title.
Philadelphia Phillies Path to the Final
The Philadelphia Phillies have had to wait a little longer for World Series success.
Last appearing in the World Series final in 2009, it has been 14 years since the Phillies lifted the World Series trophy in 2008. Since then, they have stuttered somewhat but look to be back on track this year. An 87-75 season saw them earn a spot in the NL Wild Card Series, where they progressed 2-0 over the Cardinals. A gritty 3-1 win over the Braves in the NL Division Series then saw the Phillies head to the NL Championship Series, which they also won, dropping only one game, 4-1, over the Padres.
While Philadelphia has taken the longer route to get here, it’s all on the line now against the Astros.
2022 Baseball World Series Predictions
Looking at the betting odds to win the World Series 2022, there are some great bets to be made on Major League Baseball over the next fortnight. Here are the top three bets from our World Series 2022 betting preview:
Houston Astros to Win 4-1 @ 6.50 (11/2)
While it may seem as though this World Series is anyone’s to win, given the tight outright odds by US bookmakers of 1.50 (1/2) to 2.50 (6/4), we think this series will show how much of a gap there is between the two sides.
Just compare the regular season record of the two teams. The Astros put together an impressive record of 105-56, with a 65.2% winning percentage. The Phillies, on the other hand, lost 19 more games in the regular season, going 87-75 with a win percentage of 53.7%. Add to this the fact that the Astros are unbeaten in their postseason, and we think there’s a good chance the Phillies will run out of steam and limp to a 4-1 defeat in the 2022 World Series.
With odds of 6.50 (11/2), betting on Houston Astros to win 4-1 is a great bet.
Philadelphia Phillies to Win Game One, Houston Astros to Win Series @ 5.5 (9/2)
Though we think the Astros will win this one with relative ease, don’t be surprised if Philadelphia comes out strong in the first game and pick up a win.
The Phillies have a 9-2 postseason record, with four of those wins coming on the road. This is a side that’s comfortable playing in front of hostile crowds and winning. With the first game of the World Series hosted by Houston, that’s exactly what they may do. For a side that has gone 9-2 to not win a single game in the World Series is unlikely, and if the Phillies are to win one, it makes sense that it would be upfront while they are riding the adrenaline of making the World Series for the first time in well over a decade.
Look for the Phillies to start strong, then fade away, and a bet for them to win game one, but Houston to claim the series is paying good odds at 5.5 (9/2).
Houston Astros to Win Series With -2.5 Handicap @ 4.00 (3/1)
It’s a surprise that the Astros aren’t paying higher odds to win the series outright, but betting on a -2.5 handicap gets a nice return.
For the same reasoning as above, we believe Houston will win this year’s World Series by a comfortable margin. A handicap of -2.5 gives healthy odds of 4.00 (3/1) and is a very reasonable scenario, given that they have clean-swept every team they have played in the postseason and finished their regular season with a strong win percentage.
Expect the Astros to win comfortably here, and a bet on them to win on a -2.5 handicap wouldn’t be out of line.
Bonus Pick for a Healthy Phillies vs Astros Betting
If you enjoy going against the mainstream Philadelphia Phillies vs. Houston Astros predictions, then this expert pick is for you. Here’s our prediction bonus for MLB betting:
Philadelphia Phillies to Win Series 4-1 @ 8.00 (7/1)
There’s a reason this bet is paying such high odds, and that’s because it goes against conventional wisdom that the Astros should win this one.
However, there’s an argument to be made that the Phillies could pull off a big upset here. They will be hungry for another title, having been deprived of glory for 14 years. More expectation sits on Houston due to their strong performance this year, plus the fact that they’ve made three of the last six World Series finals and have lost two of the last three. Add in the fact that the Phillies have won all of their postseason series with the loss of one game, and there’s an outside chance that this World Series could end 4-1 in favor of Philadelphia.
With a lucrative return of 8.00 (7/1), it might be worth a punt for Phillies fans who cannot lose the opportunity to beat Philadelphia online bookies with an unpredictable pick.
2022 MLB World Series Betting Tips
Let’s conclude and offer another exact score prediction as well:
- Houston Astros to Win 4-2 @ 4.50 (7/2)
- Philadelphia Phillies to Win Game One, Houston Astros to Win Series @ 5.5 (9/2)
- Houston Astros to Win Series With -2.5 Handicap @ 4.00 (3/1)
If you like the look of any of these MLB predictions to win the World Series, then you can bet today before the first game starts on the best baseball betting app. Once the series begins, there will also be a live betting option available for those who like to test out the waters first.
Frequently Asked Questions
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Who will win the World Series 2022?Bookmakers have this year’s World Series almost neck and neck, with the Houston Astros the slight favorite at 1.50 (1/2).
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Who’s ahead in the World Series?The first match begins this Friday, 28 October.
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Who won the World Series last year?The Atlanta Braves won the 2021 World Series, beating the Houston Astros 4-2.
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